PPP2CB (NM_001009552) - protein phosphatase 2 catalytic subunit beta

Serine/threonine-Protein Phosphatase 2a Catalytic Subunit Beta Isoform

Mutations Visualisation

Protein summary

This is preferred isoform of PPP2CB protein.
PPP2CB: serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
Description:

This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010].

Publication Note:
This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

Evidence data:
Transcript exon combination :: SRR1163657.541421.1, SRR1163655.37931.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350]

Strand
-
Chromosome
8
Protein
309 residues
All mutations
26
PTM sites
15
CDS
30,643,750 - 30,669,937
Transcription
30,643,125 - 30,670,352
6.15% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 5516
Uniprot
Ensembl