PRDM1 (NM_001198) - PR/SET domain 1

Pr Domain Zinc Finger Protein 1 Isoform 1

Mutations Visualisation

Protein summary

This is preferred isoform of PRDM1 protein. View all 2 isoforms
PRDM1: PR domain zinc finger protein 1 isoform 1
Description:

This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008].

Strand
+
Chromosome
6
Protein
825 residues
All mutations
139
PTM sites
10
CDS
106,534,428 - 106,555,361
Transcription
106,534,194 - 106,557,814
49.82% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 639
Uniprot
Ensembl