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KAT7 (NM_001199157) - lysine acetyltransferase 7

Histone Acetyltransferase Kat7 Isoform 4

Mutations Visualisation

Protein summary

This is an alternative isoform of KAT7 protein. View all 5 isoforms
KAT7: histone acetyltransferase KAT7 isoform 4
Description:

The protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed. [provided by RefSeq, Oct 2016].

Strand
+
Chromosome
17
Protein
501 residues
All mutations
60
PTM sites
44
CDS
47,866,196 - 47,904,864
Transcription
47,865,980 - 47,906,458
34.93% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & UniProt.
RefSeq
Entrez
gene: 11143
UniProt
Ensembl