You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020

CSNK2B (NM_001282385) - casein kinase 2 beta

Casein Kinase Ii Subunit Beta Isoform 2

Mutations Visualisation

Protein summary

This is preferred isoform of CSNK2B protein.
CSNK2B: casein kinase II subunit beta isoform 2
Description:

This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013].

Strand
+
Chromosome
6
Protein
212 residues
All mutations
22
PTM sites
21
CDS
31,634,608 - 31,637,703
Transcription
31,633,656 - 31,637,847
4.25% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & UniProt.
RefSeq
Entrez
gene: 1460
UniProt
Ensembl