BRD1 (NM_001304809) - bromodomain containing 1

Bromodomain-Containing Protein 1 Isoform 2

Mutations Visualisation

Protein summary

This is preferred isoform of BRD1 protein. View all 2 isoforms
BRD1: bromodomain-containing protein 1 isoform 2
Description:

This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schizophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2017].

Strand
-
Chromosome
22
Protein
1058 residues
All mutations
163
PTM sites
43
CDS
50,167,880 - 50,217,965
Transcription
50,166,925 - 50,219,548
40.93% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 23774
Uniprot
Ensembl