CDK2 (NM_001798) - cyclin dependent kinase 2

Cyclin-Dependent Kinase 2 Isoform 1

Mutations Visualisation

Protein summary

This is preferred isoform of CDK2 protein. View all 3 isoforms
CDK2: cyclin-dependent kinase 2 isoform 1
Description:

This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].

Strand
+
Chromosome
12
Protein
298 residues
All mutations
23
PTM sites
23
CDS
56,360,792 - 56,365,409
Transcription
56,360,552 - 56,366,573
0.0% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 1017
Uniprot
Ensembl