CSNK2A1 (NM_001895) - casein kinase 2 alpha 1

Casein Kinase Ii Subunit Alpha Isoform A

Mutations Visualisation

Protein summary

This is preferred isoform of CSNK2A1 protein. View all 3 isoforms
CSNK2A1: casein kinase II subunit alpha isoform a
Description:

Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene. [provided by RefSeq, Jul 2014].

Strand
-
Chromosome
20
Protein
391 residues
All mutations
40
PTM sites
31
CDS
464,604 - 489,195
Transcription
463,337 - 524,482
16.37% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 1457
Uniprot
Ensembl