PPP2R5C (NM_002719) - protein phosphatase 2 regulatory subunit B'gamma

Serine/threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Gamma Isoform Isoform A

Mutations Visualisation

Protein summary

This is preferred isoform of PPP2R5C protein. View all 5 isoforms
PPP2R5C: serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform a
Description:

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

Strand
+
Chromosome
14
Protein
524 residues
All mutations
63
PTM sites
11
CDS
102,276,279 - 102,391,609
Transcription
102,276,139 - 102,394,328
22.71% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 5527
Uniprot
Ensembl