You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020
MAPK11 (NM_002751) - mitogen-activated protein kinase 11
Mitogen-Activated Protein Kinase 11
Legend
Mutation impacts
direct
network-rewiring
motif-changing
proximal
distal
none
Sites
multiple types
acetylation
methylation
succinylation
sumoylation
ubiquitination
glycosylation
- C-linked
- N-linked
- O-linked
- S-linked
phosphorylation
- SARS-CoV-2
Others
Exact position of a PTM site
If you have any questions or feedback about this protein:
Contact us
Mutations Visualisation
Protein summary
This is preferred isoform of MAPK11 protein.
MAPK11:
mitogen-activated protein kinase 11
Description:
This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].
- Strand
- -
- Chromosome
- 22
- Protein
- 364 residues
- All mutations
- 38
- PTM sites
- 9
- CDS
- 50,703,376 - 50,708,721
- Transcription
- 50,702,141 - 50,708,822
External references
Mappings retrieved from NCBI & UniProt.