MAPK11 (NM_002751) - mitogen-activated protein kinase 11

Mitogen-Activated Protein Kinase 11

Mutations Visualisation

Protein summary

This is preferred isoform of MAPK11 protein.
MAPK11: mitogen-activated protein kinase 11
Description:

This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].

Strand
-
Chromosome
22
Protein
364 residues
All mutations
34
PTM sites
7
CDS
50,703,376 - 50,708,721
Transcription
50,702,141 - 50,708,822
4.67% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 5600
Uniprot
Ensembl