RAD1 (NM_002853) - RAD1 checkpoint DNA exonuclease

Cell Cycle Checkpoint Protein Rad1

Mutations Visualisation

Protein summary

This is preferred isoform of RAD1 protein.
RAD1: cell cycle checkpoint protein RAD1
Description:

This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009].

Strand
-
Chromosome
5
Protein
282 residues
All mutations
39
PTM sites
3
CDS
34,908,869 - 34,914,997
Transcription
34,905,365 - 34,915,780
6.38% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 5810
Uniprot
Ensembl