PYGB (NM_002862) - glycogen phosphorylase B
Glycogen Phosphorylase, Brain Form
Legend
Mutation impacts
Sites
- C-linked
- N-linked
- O-linked
- S-linked
- SARS-CoV-2
Others
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Mutations Visualisation
Protein summary
The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq, Jul 2008].
Publication Note:
This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Evidence data:
Transcript exon combination :: SRR1803617.211977.1, SRR1660807.231969.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348]
- Strand
- +
- Chromosome
- 20
- Protein
- 843 residues
- All mutations
- 158
- PTM sites
- 50
- CDS
- 25,228,814 - 25,277,158
- Transcription
- 25,228,705 - 25,278,648