RFC3 (NM_002915) - replication factor C subunit 3

Replication Factor C Subunit 3 Isoform 1

Mutations Visualisation

Protein summary

This is preferred isoform of RFC3 protein. View all 2 isoforms
RFC3: replication factor C subunit 3 isoform 1
Description:

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].

Strand
+
Chromosome
13
Protein
356 residues
All mutations
51
PTM sites
13
CDS
34,392,315 - 34,410,432
Transcription
34,392,205 - 34,411,644
1.4% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 5983
Uniprot
Ensembl