UBA52 (NM_003333) - ubiquitin A-52 residue ribosomal protein fusion product 1

Ubiquitin-60s Ribosomal Protein L40 Isoform 1 Precursor

Mutations Visualisation

Protein summary

This is preferred isoform of UBA52 protein. View all 2 isoforms
UBA52: ubiquitin-60S ribosomal protein L40 isoform 1 precursor
Description:

Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived from this gene are present in the genome. [provided by RefSeq, Jul 2008].

Publication Note:
This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

Evidence data:
Transcript exon combination :: SRR1803615.56978.1, SRR1660809.116956.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348]

Strand
+
Chromosome
19
Protein
128 residues
All mutations
16
PTM sites
19
CDS
18,684,110 - 18,685,960
Transcription
18,682,613 - 18,688,270
1.56% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 7311
Uniprot
Ensembl