PIP4K2B (NM_003559) - phosphatidylinositol-5-phosphate 4-kinase type 2 beta

Phosphatidylinositol 5-Phosphate 4-Kinase Type-2 Beta

Mutations Visualisation

Protein summary

This is preferred isoform of PIP4K2B protein.
PIP4K2B: phosphatidylinositol 5-phosphate 4-kinase type-2 beta
Description:

The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor. [provided by RefSeq, Jul 2008].

Publication Note:
This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

Evidence data:
Transcript exon combination :: U85245.1, SRR1660809.164419.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350]

Strand
-
Chromosome
17
Protein
416 residues
All mutations
45
PTM sites
10
CDS
36,925,943 - 36,955,677
Transcription
36,921,943 - 36,956,158
20.43% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 8396
Uniprot
Ensembl