AURKB (NM_004217) - aurora kinase B

Aurora Kinase B Isoform 1

Mutations Visualisation

Protein summary

This is preferred isoform of AURKB protein. View all 9 isoforms
AURKB: aurora kinase B isoform 1
Description:

This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015].

Strand
-
Chromosome
17
Protein
344 residues
All mutations
57
PTM sites
31
CDS
8,108,188 - 8,113,542
Transcription
8,108,048 - 8,113,944
21.51% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 9212
Uniprot
Ensembl