TAF13 (NM_005645) - TATA-box binding protein associated factor 13

Transcription Initiation Factor Tfiid Subunit 13

Mutations Visualisation

Protein summary

This is preferred isoform of TAF13 protein.
TAF13: transcription initiation factor TFIID subunit 13
Description:

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6. [provided by RefSeq, Jul 2008].

Publication Note:
This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

Evidence data:
Transcript exon combination :: AU280379.1, SRR1660807.302993.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2142670 [ECO:0000350]

Strand
-
Chromosome
1
Protein
124 residues
All mutations
13
PTM sites
2
CDS
109,607,144 - 109,618,569
Transcription
109,606,997 - 109,618,624
31.45% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 6884
Uniprot
Ensembl