EXO1 (NM_006027) - exonuclease 1

Exonuclease 1 Isoform B

Mutations Visualisation

Protein summary

This is preferred isoform of EXO1 protein. View all 3 isoforms
EXO1: exonuclease 1 isoform b
Description:

This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008].

Strand
+
Chromosome
1
Protein
846 residues
All mutations
181
PTM sites
33
CDS
242,013,727 - 242,052,902
Transcription
242,012,032 - 242,053,241
57.09% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 9156
Uniprot
Ensembl