POU4F1 (NM_006237) - POU class 4 homeobox 1

Pou Domain, Class 4, Transcription Factor 1

Mutations Visualisation

Protein summary

This is preferred isoform of POU4F1 protein.
POU4F1: POU domain, class 4, transcription factor 1
Description:

This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias. [provided by RefSeq, Mar 2012].

Publication Note:
This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

Evidence data:
Transcript exon combination :: L20433.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093 [ECO:0000348]

Strand
-
Chromosome
13
Protein
419 residues
All mutations
40
PTM sites
3
CDS
79,175,549 - 79,177,461
Transcription
79,173,229 - 79,177,695
65.63% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 5457
Uniprot
Ensembl