KAT5 (NM_006388) - lysine acetyltransferase 5

Histone Acetyltransferase Kat5 Isoform 2

Mutations Visualisation

Protein summary

This is preferred isoform of KAT5 protein. View all 4 isoforms
KAT5: histone acetyltransferase KAT5 isoform 2
Description:

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008].

Strand
+
Chromosome
11
Protein
513 residues
All mutations
54
PTM sites
20
CDS
65,479,738 - 65,486,652
Transcription
65,479,472 - 65,487,077
19.1% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 10524
Uniprot
Ensembl