TAF9B (NM_015975) - TATA-box binding protein associated factor 9b

Transcription Initiation Factor Tfiid Subunit 9b

Mutations Visualisation

Protein summary

This is preferred isoform of TAF9B protein.
TAF9B: transcription initiation factor TFIID subunit 9B
Description:

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process. [provided by RefSeq, Jul 2008].

Evidence data:
Transcript exon combination :: SRR1803617.158673.1, SRR1163658.498744.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350]

Strand
-
Chromosome
X
Protein
251 residues
All mutations
38
PTM sites
15
CDS
77,387,106 - 77,395,108
Transcription
77,385,244 - 77,395,179
49.4% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 51616
Uniprot
Ensembl