KMT5A (NM_020382) - lysine methyltransferase 5A

N-Lysine Methyltransferase Kmt5a Isoform 1

Mutations Visualisation

Protein summary

This is preferred isoform of KMT5A protein.
KMT5A: N-lysine methyltransferase KMT5A isoform 1
Description:

The protein encoded by this gene is a protein-lysine N-methyltransferase that can monomethylate Lys-20 of histone H4 to effect transcriptional repression of some genes. The encoded protein is required for cell proliferation and plays a role in chromatin condensation. [provided by RefSeq, May 2016].

Strand
+
Chromosome
12
Protein
352 residues
All mutations
38
PTM sites
10
CDS
123,868,745 - 123,892,250
Transcription
123,868,703 - 123,893,900
38.64% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 387893
Uniprot
Ensembl