UBC (NM_021009) - ubiquitin C

Polyubiquitin-C

Mutations Visualisation

Protein summary

This is preferred isoform of UBC protein.
UBC: polyubiquitin-C
Description:

This gene represents a ubiquitin gene, ubiquitin C. The encoded protein is a polyubiquitin precursor. Conjugation of ubiquitin monomers or polymers can lead to various effects within a cell, depending on the residues to which ubiquitin is conjugated. Ubiquitination has been associated with protein degradation, DNA repair, cell cycle regulation, kinase modification, endocytosis, and regulation of other cell signaling pathways. [provided by RefSeq, Aug 2010].

Publication Note:
This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

Evidence data:
Transcript exon combination :: BC039193.1, AB009010.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348]

Strand
-
Chromosome
12
Protein
685 residues
All mutations
79
PTM sites
143
CDS
125,396,259 - 125,398,317
Transcription
125,396,190 - 125,399,587
0.0% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 7316
Uniprot
Ensembl