HIPK2 (NM_022740) - homeodomain interacting protein kinase 2

Homeodomain-Interacting Protein Kinase 2 Isoform 1

Mutations Visualisation

Protein summary

This is preferred isoform of HIPK2 protein. View all 2 isoforms
HIPK2: homeodomain-interacting protein kinase 2 isoform 1
Description:

This gene encodes a conserved serine/threonine kinase that is a member of the homeodomain-interacting protein kinase family. The encoded protein interacts with homeodomain transcription factors and many other transcription factors such as p53, and can function as both a corepressor and a coactivator depending on the transcription factor and its subcellular localization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

Strand
-
Chromosome
7
Protein
1198 residues
All mutations
159
PTM sites
31
CDS
139,257,672 - 139,477,422
Transcription
139,246,315 - 139,477,693
69.45% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 28996
Uniprot
Ensembl