TAF3 (NM_031923) - TATA-box binding protein associated factor 3

Transcription Initiation Factor Tfiid Subunit 3

Mutations Visualisation

Protein summary

This is preferred isoform of TAF3 protein.
TAF3: transcription initiation factor TFIID subunit 3
Description:

The highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA box-binding protein (TBP; MIM 600075) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors (Gangloff et al., 2001 [PubMed 11438666]).[supplied by OMIM, May 2009]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

Publication Note:
This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

Evidence data:
RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348]

Strand
+
Chromosome
10
Protein
929 residues
All mutations
119
PTM sites
46
CDS
7,860,672 - 8,056,714
Transcription
7,860,466 - 8,057,016
78.36% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 83860
Uniprot
Ensembl