ING5 (NM_032329) - inhibitor of growth family member 5

Inhibitor Of Growth Protein 5 Isoform 1

Mutations Visualisation

Protein summary

This is preferred isoform of ING5 protein.
ING5: inhibitor of growth protein 5 isoform 1
Description:

This gene encodes a tumor suppressor protein that inhibits cell growth and induces apoptosis. This protein contains a PHD-type zinc finger. It interacts with tumor suppressor p53 and p300, a component of the histone acetyl transferase complex, suggesting a role in transcriptional regulation. Alternative splicing and the use of multiple promoters and 3' terminal exons results in multiple transcript variants. [provided by RefSeq, Aug 2016].

Publication Note:
This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

Evidence data:
Transcript exon combination :: SRR1163655.286845.1, SRR1803611.33000.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348]

Strand
+
Chromosome
2
Protein
240 residues
All mutations
22
PTM sites
11
CDS
242,641,480 - 242,664,446
Transcription
242,641,455 - 242,668,896
27.92% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 84289
Uniprot
Ensembl