RICTOR (NM_152756) - RPTOR independent companion of MTOR complex 2

Rapamycin-Insensitive Companion Of Mtor Isoform 1

Mutations Visualisation

Protein summary

This is preferred isoform of RICTOR protein. View all 3 isoforms
RICTOR: rapamycin-insensitive companion of mTOR isoform 1
Description:

RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008].

Strand
-
Chromosome
5
Protein
1708 residues
All mutations
193
PTM sites
99
CDS
38,942,405 - 39,074,479
Transcription
38,938,022 - 39,074,510
40.81% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & Uniprot.
RefSeq
Entrez
gene: 253260
Uniprot
Ensembl