You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020

HIPK1 (NM_181358) - homeodomain interacting protein kinase 1

Homeodomain-Interacting Protein Kinase 1 Isoform 4

Mutations Visualisation

Protein summary

This is an alternative isoform of HIPK1 protein. View all 4 isoforms
HIPK1: homeodomain-interacting protein kinase 1 isoform 4
Description:

The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms. [provided by RefSeq, Jul 2008].

Strand
+
Chromosome
1
Protein
816 residues
All mutations
102
PTM sites
23
CDS
114,497,254 - 114,516,134
Transcription
114,496,498 - 114,520,491
81.62% of sequence is predicted to be disordered

External references

Mappings retrieved from NCBI & UniProt.
RefSeq
Entrez
gene: 204851
UniProt
Ensembl