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Mutation:
MSH6 P768S
Summary
Isoform:
Position:
768
Ref:
P
Mutation:
S
PTM impact:
network-rewiring
PTM affected:
2
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
Hereditary cancer-predisposing syndrome
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 767T
Affected site:
Position: 767
Residue: T
Type: phosphorylation
Only loss of PTM site:
CDK1 (probability p=0.885)
Site: 767T (phosphorylation)
Position in motif: 1
Other known mutations affecting this site
PTM Site: 771K
Affected site:
Position: 771
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
External references
dbSNP:
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