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Mutation:
PDE3A Q546E
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
[0.0199681]
PTM Site: 541K
Affected site:
Position: 541
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 546E | PASSLVSKISAV[Q/E]QFP | 5 |
distal
|
PTM Site: 550S
Affected site:
Position: 550
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 552V | SAVQFPESA[D/V]DTTAKQ | 2 |
proximal
|
| 546E | SAV[Q/E]QFPESADTTAKQ | 4 |
distal
|
| 549Q | SAVQFP[E/Q]ESADTTAKQ | 1 |
proximal
|
PTM Site: 553T
Affected site:
Position: 553
Residue: T
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 552V | QFPESA[D/V]DTTAKQSLG | 1 |
proximal
|
| 559R | QFPESADTTAKQS[L/R]LG | 6 |
distal
|
| 549Q | QFP[E/Q]ESADTTAKQSLG | 4 |
distal
|
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