MBP I143F

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Mutation:

Summary

Isoform:

NM_001025092

Position:

143

Ref:

Mutation:

PTM impact:

proximal

PTM affected:

Kinases:

PRKCA

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

Lymph-CLL

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 139T

Affected site:

Position: 139

Residue: T

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
142R	KGVDAQGTLS[K/R]KIFKL	3	distal
145M	KGVDAQGTLSKIF[K/M]KL	6	distal
142E	KGVDAQGTLS[K/E]KIFKL	3	network-rewiring
135N	KGV[D/N]DAQGTLSKIFKL	4	distal
143F	KGVDAQGTLSK[I/F]IFKL	4	distal

PTM Site: 141S

Affected site:

Position: 141

Residue: S

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
147E	VDAQGTLSKIFKL[G/E]GG	6	distal
147R	VDAQGTLSKIFKL[G/R]GG	6	distal
142R	VDAQGTLS[K/R]KIFKLGG	1	proximal
145M	VDAQGTLSKIF[K/M]KLGG	4	distal
142E	VDAQGTLS[K/E]KIFKLGG	1	proximal
135N	V[D/N]DAQGTLSKIFKLGG	6	distal
143F	VDAQGTLSK[I/F]IFKLGG	2	proximal

If you have any questions or feedback about this mutation: