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Mutation:
CEP63 Q151R
Summary
Isoform:
Position:
151
Ref:
Q
Mutation:
R
PTM impact:
proximal
PTM affected:
3
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
[0.0199681]
PTM Site: 145K
Affected site:
Position: 145
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 146T | EIERLTAK[I/T]IEEFRQK | 1 |
proximal
|
| 139T | E[I/T]IERLTAKIEEFRQK | 6 |
distal
|
| 144T | EIERLT[A/T]AKIEEFRQK | 1 |
proximal
|
| 151R | EIERLTAKIEEFR[Q/R]QK | 6 |
distal
|
| 150C | EIERLTAKIEEF[R/C]RQK | 5 |
distal
|
| 140K | EI[E/K]ERLTAKIEEFRQK | 5 |
distal
|
| 145E | EIERLTA[K/E]KIEEFRQK | 0 |
direct
|
PTM Site: 152K
Affected site:
Position: 152
Residue: K
Type: ubiquitination
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 146T | K[I/T]IEEFRQKSLDWEKQ | 6 |
distal
|
| 151R | KIEEFR[Q/R]QKSLDWEKQ | 1 |
proximal
|
| 150C | KIEEF[R/C]RQKSLDWEKQ | 2 |
proximal
|
| 153L | KIEEFRQK[S/L]SLDWEKQ | 1 |
proximal
|
PTM Site: 158K
Affected site:
Position: 158
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 160S | QKSLDWEKQ[R/S]RLIYQQ | 2 |
proximal
|
| 162T | QKSLDWEKQRL[I/T]IYQQ | 4 |
distal
|
| 153L | QK[S/L]SLDWEKQRLIYQQ | 5 |
distal
|
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