You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020
Mutation:
CEP63 S153L
Summary
Isoform:
Position:
153
Ref:
S
Mutation:
L
PTM impact:
proximal
PTM affected:
2
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
SKCM, BLCA
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 152K
Affected site:
Position: 152
Residue: K
Type: ubiquitination
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 146T | K[I/T]IEEFRQKSLDWEKQ | 6 |
distal
|
| 151R | KIEEFR[Q/R]QKSLDWEKQ | 1 |
proximal
|
| 150C | KIEEF[R/C]RQKSLDWEKQ | 2 |
proximal
|
| 153L | KIEEFRQK[S/L]SLDWEKQ | 1 |
proximal
|
PTM Site: 158K
Affected site:
Position: 158
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 160S | QKSLDWEKQ[R/S]RLIYQQ | 2 |
proximal
|
| 162T | QKSLDWEKQRL[I/T]IYQQ | 4 |
distal
|
| 153L | QK[S/L]SLDWEKQRLIYQQ | 5 |
distal
|
If you have any questions or feedback about this mutation:
Contact us