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Summary

Isoform:
Position:
41
Ref:
P
Mutation:
S
PTM impact:
distal
PTM affected:
2
Kinases:

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

[0.0084]

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 45K

Affected site:

Position: 45
Residue: K
Type: ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation In sequence Distance Impact
43V RIRPL[A/V]AEKTGICKIR 2
proximal
41S RIR[P/S]PLAEKTGICKIR 4
distal
48M RIRPLAEKTG[I/M]ICKIR 3
distal

PTM Site: 46T

Affected site:

Position: 46
Residue: T
Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation In sequence Distance Impact
43V IRPL[A/V]AEKTGICKIRP 3
distal
41S IR[P/S]PLAEKTGICKIRP 5
distal
48M IRPLAEKTG[I/M]ICKIRP 2
proximal
52W IRPLAEKTGICKI[R/W]RP 6
distal

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