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Mutation:
BCLAF1 P236L
Summary
Isoform:
Position:
236
Ref:
P
Mutation:
L
PTM impact:
proximal
PTM affected:
2
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
HNSC
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 230S
Affected site:
Position: 230
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 232V | PRSPHSPSP[I/V]IATPPS | 2 |
proximal
|
| 228R | PRSPH[S/R]SPSPIATPPS | 2 |
network-rewiring
|
| 228N | PRSPH[S/N]SPSPIATPPS | 2 |
proximal
|
| 224I | P[R/I]RSPHSPSPIATPPS | 6 |
distal
|
| 236H | PRSPHSPSPIATP[P/H]PS | 6 |
distal
|
| 228I | PRSPH[S/I]SPSPIATPPS | 2 |
proximal
|
| 230L | PRSPHSP[S/L]SPIATPPS | 0 |
direct
|
| 236L | PRSPHSPSPIATP[P/L]PS | 6 |
distal
|
| 235L | PRSPHSPSPIAT[P/L]PPS | 5 |
distal
|
PTM Site: 234T
Affected site:
Position: 234
Residue: T
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 232V | HSPSP[I/V]IATPPSQSSS | 2 |
proximal
|
| 228R | H[S/R]SPSPIATPPSQSSS | 6 |
distal
|
| 228N | H[S/N]SPSPIATPPSQSSS | 6 |
distal
|
| 236H | HSPSPIATP[P/H]PSQSSS | 2 |
proximal
|
| 228I | H[S/I]SPSPIATPPSQSSS | 6 |
distal
|
| 240P | HSPSPIATPPSQS[S/P]SS | 6 |
distal
|
| 237R | HSPSPIATPP[S/R]SQSSS | 3 |
network-rewiring
|
| 230L | HSP[S/L]SPIATPPSQSSS | 4 |
distal
|
| 236L | HSPSPIATP[P/L]PSQSSS | 2 |
proximal
|
| 235L | HSPSPIAT[P/L]PPSQSSS | 1 |
network-rewiring
|
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