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Summary

Isoform:
Position:
74
Ref:
G
Mutation:
D
PTM impact:
network-rewiring
PTM affected:
2
Kinases:

Clinical Information

Cancer types: (TCGA MC3)

BLCA

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 76S

Affected site:

Position: 76
Residue: S
Type: phosphorylation

Only gain of PTM site:

PLK1 (probability p=0.891)
Site: 76S (phosphorylation)
Position in motif: -2

Other known mutations affecting this site

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Mutation
In sequence
Distance
Impact
78A SSHKPGSSP[S/A]SSPREK 2
proximal
74D SSHKP[G/D]GSSPSSPREK 2
network-rewiring
Showing 1 to 2 of 2 rows

PTM Site: 78S

Affected site:

Position: 78
Residue: S
Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

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Mutation
In sequence
Distance
Impact
78A HKPGSSP[S/A]SSPREKDL 0
direct
74D HKP[G/D]GSSPSSPREKDL 4
distal
Showing 1 to 2 of 2 rows

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