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Summary

Isoform:
Position:
78
Ref:
S
Mutation:
A
PTM impact:
direct
PTM affected:
3
Kinases:

Clinical Information

Cancer types: (TCGA MC3)

LUAD

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 76S

Affected site:

Position: 76
Residue: S
Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation In sequence Distance Impact
78A SSHKPGSSP[S/A]SSPREK 2
proximal
74D SSHKP[G/D]GSSPSSPREK 2
network-rewiring

PTM Site: 78S

Affected site:

Position: 78
Residue: S
Type: phosphorylation

Impact:

direct

Other known mutations affecting this site

Mutation In sequence Distance Impact
78A HKPGSSP[S/A]SSPREKDL 0
direct
74D HKP[G/D]GSSPSSPREKDL 4
distal

PTM Site: 83K

Affected site:

Position: 83
Residue: K
Type: ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation In sequence Distance Impact
85P SPSSPREKD[L/P]LLSMLC 2
proximal
78A SP[S/A]SSPREKDLLSMLC 5
distal

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