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Mutation:
FLNA R51C
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
Ovary-AdenoCA
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 48T
Affected site:
Position: 48
Residue: T
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
Mutation | In sequence | Distance | Impact |
---|---|---|---|
43N | WK[K/N]KIQQNTFTRWCNE | 5 |
distal
|
42R | W[K/R]KKIQQNTFTRWCNE | 6 |
distal
|
54K | WKKIQQNTFTRWC[N/K]NE | 6 |
distal
|
51C | WKKIQQNTFT[R/C]RWCNE | 3 |
distal
|
PTM Site: 50T
Affected site:
Position: 50
Residue: T
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
Mutation | In sequence | Distance | Impact |
---|---|---|---|
56Q | KIQQNTFTRWCNE[H/Q]HL | 6 |
distal
|
55K | KIQQNTFTRWCN[E/K]EHL | 5 |
distal
|
54K | KIQQNTFTRWC[N/K]NEHL | 4 |
distal
|
51C | KIQQNTFT[R/C]RWCNEHL | 1 |
proximal
|
PTM Site: 58K
Affected site:
Position: 58
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
Mutation | In sequence | Distance | Impact |
---|---|---|---|
56Q | RWCNE[H/Q]HLKCVSKRIA | 2 |
proximal
|
55K | RWCN[E/K]EHLKCVSKRIA | 3 |
distal
|
54K | RWC[N/K]NEHLKCVSKRIA | 4 |
distal
|
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