FLNA E55K

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Mutation:

Summary

Isoform:

NM_001110556

Position:

Ref:

Mutation:

PTM impact:

distal

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

CESC

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 48T

Affected site:

Position: 48

Residue: T

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
43N	WK[K/N]KIQQNTFTRWCNE	5	distal
42R	W[K/R]KKIQQNTFTRWCNE	6	distal
54K	WKKIQQNTFTRWC[N/K]NE	6	distal
51C	WKKIQQNTFT[R/C]RWCNE	3	distal

PTM Site: 50T

Affected site:

Position: 50

Residue: T

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
56Q	KIQQNTFTRWCNE[H/Q]HL	6	distal
55K	KIQQNTFTRWCN[E/K]EHL	5	distal
54K	KIQQNTFTRWC[N/K]NEHL	4	distal
51C	KIQQNTFT[R/C]RWCNEHL	1	proximal

PTM Site: 58K

Affected site:

Position: 58

Residue: K

Type: ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
56Q	RWCNE[H/Q]HLKCVSKRIA	2	proximal
55K	RWCN[E/K]EHLKCVSKRIA	3	distal
54K	RWC[N/K]NEHLKCVSKRIA	4	distal

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