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Mutation:
TP53 M1V
Summary
Isoform:
Position:
1
Ref:
M
Mutation:
V
PTM impact:
distal
PTM affected:
1
Kinases:
CSNK1A1
Clinical Information
Cancer types: (TCGA MC3)
HNSC
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 6S
Affected site:
Position: 6
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 12L | --MEEPQSDPSVE[P/L]PP | 6 |
distal
|
| 12R | --MEEPQSDPSVE[P/R]PP | 6 |
distal
|
| 12H | --MEEPQSDPSVE[P/H]PP | 6 |
distal
|
| 11Q | --MEEPQSDPSV[E/Q]EPP | 5 |
distal
|
| 11K | --MEEPQSDPSV[E/K]EPP | 5 |
distal
|
| 10G | --MEEPQSDPS[V/G]VEPP | 4 |
distal
|
| 10F | --MEEPQSDPS[V/F]VEPP | 4 |
distal
|
| 10L | --MEEPQSDPS[V/L]VEPP | 4 |
distal
|
| 10I | --MEEPQSDPS[V/I]VEPP | 4 |
distal
|
| 9R | --MEEPQSDP[S/R]SVEPP | 3 |
distal
|
| 9N | --MEEPQSDP[S/N]SVEPP | 3 |
distal
|
| 8L | --MEEPQSD[P/L]PSVEPP | 2 |
proximal
|
| 8T | --MEEPQSD[P/T]PSVEPP | 2 |
proximal
|
| 7E | --MEEPQS[D/E]DPSVEPP | 1 |
proximal
|
| 7H | --MEEPQS[D/H]DPSVEPP | 1 |
proximal
|
| 5R | --MEEP[Q/R]QSDPSVEPP | 1 |
proximal
|
| 4L | --MEE[P/L]PQSDPSVEPP | 2 |
proximal
|
| 4R | --MEE[P/R]PQSDPSVEPP | 2 |
network-rewiring
|
| 3G | --ME[E/G]EPQSDPSVEPP | 3 |
distal
|
| 3Q | --ME[E/Q]EPQSDPSVEPP | 3 |
distal
|
| 3K | --ME[E/K]EPQSDPSVEPP | 3 |
distal
|
| 2G | --M[E/G]EEPQSDPSVEPP | 4 |
distal
|
| 2K | --M[E/K]EEPQSDPSVEPP | 4 |
distal
|
| 1V | --[M/V]MEEPQSDPSVEPP | 5 |
distal
|
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