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Mutation:
TP53 R49H
Summary
Isoform:
Position:
49
Ref:
R
Mutation:
H
PTM impact:
network-rewiring
PTM affected:
1
Kinases:
AURKB
Clinical Information
Cancer types: (TCGA MC3)
UCEC, COAD, LGG, BLCA
Cancer types: (PCAWG)
Panc-AdenoCA
Disease Annotations: (ClinVar)
Li-Fraumeni syndrome, Hereditary cancer-predisposing syndrome
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 51S
Affected site:
Position: 51
Residue: S
Type: phosphorylation
Only loss of PTM site:
ROCK1 (probability p=0.853)
Site: 51S (phosphorylation)
Position in motif: -2
Other known mutations affecting this site
External references
dbSNP:
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