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Mutation:
TP53 R49L
Summary
Isoform:
Position:
49
Ref:
R
Mutation:
L
PTM impact:
network-rewiring
PTM affected:
1
Kinases:
AURKB
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
Li-Fraumeni syndrome, Glioma susceptibility 1
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 51S
Affected site:
Position: 51
Residue: S
Type: phosphorylation
Only loss of PTM site:
ROCK1 (probability p=0.872)
Site: 51S (phosphorylation)
Position in motif: -2
Other known mutations affecting this site
External references
dbSNP:
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