SAFB K423N

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Mutation:

Summary

Isoform:

NM_001201339

Position:

423

Ref:

Mutation:

PTM impact:

direct

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

LUAD

Cancer types: (PCAWG)

Lung-AdenoCA

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 416T

Affected site:

Position: 416

Residue: T

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
415T	WVSGLS[S/T]STTRATDLK	1	proximal
415Y	WVSGLS[S/Y]STTRATDLK	1	proximal

PTM Site: 423K

Affected site:

Position: 423

Residue: K

Type: acetylation, ubiquitination

Impact:

direct

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
429C	TTRATDLKNLFSK[Y/C]YG	6	distal
423N	TTRATDL[K/N]KNLFSKYG	0	direct
429H	TTRATDLKNLFSK[Y/H]YG	6	distal

PTM Site: 428K

Affected site:

Position: 428

Residue: K

Type: acetylation, ubiquitination

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
429C	DLKNLFSK[Y/C]YGKVVGA	1	proximal
423N	DL[K/N]KNLFSKYGKVVGA	5	distal
429H	DLKNLFSK[Y/H]YGKVVGA	1	proximal

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