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Mutation:
CTNND1 R182C
Summary
Isoform:
Position:
182
Ref:
R
Mutation:
C
PTM impact:
proximal
PTM affected:
5
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0156]
Minor Allele Frequency: (1000 Genomes)
[0.0199681]
PTM Site: 176S
Affected site:
Position: 176
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 182C | GGSDNYGSLSRVT[R/C]RI | 6 |
distal
|
| 179Q | GGSDNYGSLS[R/Q]RVTRI | 3 |
distal
|
PTM Site: 178S
Affected site:
Position: 178
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 182C | SDNYGSLSRVT[R/C]RIEE | 4 |
distal
|
| 179Q | SDNYGSLS[R/Q]RVTRIEE | 1 |
network-rewiring
|
PTM Site: 181T
Affected site:
Position: 181
Residue: T
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 182C | YGSLSRVT[R/C]RIEERYR | 1 |
proximal
|
| 185G | YGSLSRVTRIE[E/G]ERYR | 4 |
distal
|
| 179Q | YGSLS[R/Q]RVTRIEERYR | 2 |
network-rewiring
|
PTM Site: 187Y
Affected site:
Position: 187
Residue: Y
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 182C | VT[R/C]RIEERYRPSMEGY | 5 |
distal
|
| 185G | VTRIE[E/G]ERYRPSMEGY | 2 |
proximal
|
PTM Site: 188R
Affected site:
Position: 188
Residue: R
Type: methylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 182C | T[R/C]RIEERYRPSMEGYR | 6 |
distal
|
| 185G | TRIE[E/G]ERYRPSMEGYR | 3 |
distal
|
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