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Mutation:

TRA2B S184P

Summary

Isoform:
NM_001243879
Position:
184
Ref:
S
Mutation:
P
PTM impact:
direct
PTM affected:
6
Kinases:

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

no data

Minor Allele Frequency: (1000 Genomes)

[0.0199681]

PTM Site: 178S

Affected site:

Position: 178
Residue: S
Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation In sequence Distance Impact
184P RGGYRSRSRSRSY[S/P]SP 6
distal
184L RGGYRSRSRSRSY[S/L]SP 6
distal
177L RGGYRS[R/L]RSRSRSYSP 1
proximal
181G RGGYRSRSRS[R/G]RSYSP 3
distal

PTM Site: 180S

Affected site:

Position: 180
Residue: S
Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation In sequence Distance Impact
184P GYRSRSRSRSY[S/P]SPRR 4
distal
184L GYRSRSRSRSY[S/L]SPRR 4
distal
177L GYRS[R/L]RSRSRSYSPRR 3
network-rewiring
181G GYRSRSRS[R/G]RSYSPRR 1
proximal

PTM Site: 182S

Affected site:

Position: 182
Residue: S
Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation In sequence Distance Impact
184P RSRSRSRSY[S/P]SPRRY- 2
proximal
184L RSRSRSRSY[S/L]SPRRY- 2
proximal
177L RS[R/L]RSRSRSYSPRRY- 5
distal
181G RSRSRS[R/G]RSYSPRRY- 1
proximal

PTM Site: 183Y

Affected site:

Position: 183
Residue: Y
Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation In sequence Distance Impact
184P SRSRSRSY[S/P]SPRRY-- 1
proximal
184L SRSRSRSY[S/L]SPRRY-- 1
proximal
177L S[R/L]RSRSRSYSPRRY-- 6
distal
181G SRSRS[R/G]RSYSPRRY-- 2
proximal

PTM Site: 184S

Affected site:

Position: 184
Residue: S
Type: phosphorylation

Impact:

direct

Other known mutations affecting this site

Mutation In sequence Distance Impact
184P RSRSRSY[S/P]SPRRY--- 0
direct
184L RSRSRSY[S/L]SPRRY--- 0
direct
181G RSRS[R/G]RSYSPRRY--- 3
network-rewiring

PTM Site: 188Y

Affected site:

Position: 188
Residue: Y
Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation In sequence Distance Impact
184P RSY[S/P]SPRRY------- 4
distal
184L RSY[S/L]SPRRY------- 4
distal

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