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Mutation:
PYGB A2T
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
[0.0077]
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 2A
Affected site:
Position: 2
Residue: A
Type: acetylation
Impact:
directOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 2T | ------M[A/T]AKPLTDSE | 0 |
direct
|
| 4S | ------MAK[P/S]PLTDSE | 2 |
proximal
|
| 8C | ------MAKPLTD[S/C]SE | 6 |
distal
|
| 7Y | ------MAKPLT[D/Y]DSE | 5 |
distal
|
PTM Site: 3K
Affected site:
Position: 3
Residue: K
Type: ubiquitination
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 2T | -----M[A/T]AKPLTDSEK | 1 |
proximal
|
| 4S | -----MAK[P/S]PLTDSEK | 1 |
proximal
|
| 8C | -----MAKPLTD[S/C]SEK | 5 |
distal
|
| 7Y | -----MAKPLT[D/Y]DSEK | 4 |
distal
|
PTM Site: 6T
Affected site:
Position: 6
Residue: T
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 2T | --M[A/T]AKPLTDSEKRKQ | 4 |
distal
|
| 4S | --MAK[P/S]PLTDSEKRKQ | 2 |
proximal
|
| 8C | --MAKPLTD[S/C]SEKRKQ | 2 |
proximal
|
| 7Y | --MAKPLT[D/Y]DSEKRKQ | 1 |
proximal
|
PTM Site: 8S
Affected site:
Position: 8
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 2T | M[A/T]AKPLTDSEKRKQIS | 6 |
distal
|
| 4S | MAK[P/S]PLTDSEKRKQIS | 4 |
distal
|
| 8C | MAKPLTD[S/C]SEKRKQIS | 0 |
direct
|
| 7Y | MAKPLT[D/Y]DSEKRKQIS | 1 |
proximal
|
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