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Mutation:
GIPC1 G237D
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
[0.0199681]
PTM Site: 232S
Affected site:
Position: 232
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 238S | SAGGRPGSGPQLG[T/S]TG | 6 |
distal
|
| 231S | SAGGRP[G/S]GSGPQLGTG | 1 |
proximal
|
| 226V | S[A/V]AGGRPGSGPQLGTG | 6 |
distal
|
| 238P | SAGGRPGSGPQLG[T/P]TG | 6 |
distal
|
| 237D | SAGGRPGSGPQL[G/D]GTG | 5 |
distal
|
PTM Site: 238T
Affected site:
Position: 238
Residue: T
Type: phosphorylation
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 238S | GSGPQLG[T/S]TGRGTLRL | 0 |
direct
|
| 238P | GSGPQLG[T/P]TGRGTLRL | 0 |
direct
|
| 237D | GSGPQL[G/D]GTGRGTLRL | 1 |
proximal
|
PTM Site: 240R
Affected site:
Position: 240
Residue: R
Type: methylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 238S | GPQLG[T/S]TGRGTLRLRS | 2 |
proximal
|
| 238P | GPQLG[T/P]TGRGTLRLRS | 2 |
proximal
|
| 237D | GPQL[G/D]GTGRGTLRLRS | 3 |
distal
|
PTM Site: 242T
Affected site:
Position: 242
Residue: T
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 238S | QLG[T/S]TGRGTLRLRSRG | 4 |
distal
|
| 248W | QLGTGRGTLRLRS[R/W]RG | 6 |
distal
|
| 238P | QLG[T/P]TGRGTLRLRSRG | 4 |
distal
|
| 237D | QL[G/D]GTGRGTLRLRSRG | 5 |
distal
|
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