GIPC1 G231S

You are viewing an updated version (2021) of the ActiveDriverDB. To view the previous version please visit activedriverdb.org/v2020

Mutation:

Summary

Isoform:

NM_005716

Position:

231

Ref:

Mutation:

PTM impact:

proximal

PTM affected:

Kinases:

Clinical Information

Cancer types: (TCGA MC3)

no data

Cancer types: (PCAWG)

no data

Disease Annotations: (ClinVar)

no data

Minor Allele Frequency: (ESP6500)

[0.0155]

Minor Allele Frequency: (1000 Genomes)

no data

PTM Site: 225S

Affected site:

Position: 225

Residue: S

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
231S	FDMISQRSAGGRP[G/S]GS	6	distal
226V	FDMISQRS[A/V]AGGRPGS	1	proximal
224C	FDMISQ[R/C]RSAGGRPGS	1	proximal

PTM Site: 232S

Affected site:

Position: 232

Residue: S

Type: phosphorylation

Impact:

proximal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
238S	SAGGRPGSGPQLG[T/S]TG	6	distal
231S	SAGGRP[G/S]GSGPQLGTG	1	proximal
226V	S[A/V]AGGRPGSGPQLGTG	6	distal
238P	SAGGRPGSGPQLG[T/P]TG	6	distal
237D	SAGGRPGSGPQL[G/D]GTG	5	distal

PTM Site: 238T

Affected site:

Position: 238

Residue: T

Type: phosphorylation

Impact:

distal

Other known mutations affecting this site

Mutation	In sequence	Distance	Impact
238S	GSGPQLG[T/S]TGRGTLRL	0	direct
238P	GSGPQLG[T/P]TGRGTLRL	0	direct
237D	GSGPQL[G/D]GTGRGTLRL	1	proximal

If you have any questions or feedback about this mutation: