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Mutation:
FMNL1 F681L
Summary
Clinical Information
Cancer types: (TCGA MC3)
BLCA
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 675S
Affected site:
Position: 675
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 681L | VLQELDMSDFEEQ[F/L]FK | 6 |
distal
|
PTM Site: 682K
Affected site:
Position: 682
Residue: K
Type: ubiquitination
Impact:
proximalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 682R | SDFEEQF[K/R]KTKSQGPS | 0 |
direct
|
| 681L | SDFEEQ[F/L]FKTKSQGPS | 1 |
proximal
|
PTM Site: 684K
Affected site:
Position: 684
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 682R | FEEQF[K/R]KTKSQGPSLD | 2 |
proximal
|
| 681L | FEEQ[F/L]FKTKSQGPSLD | 3 |
distal
|
PTM Site: 685S
Affected site:
Position: 685
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 682R | EEQF[K/R]KTKSQGPSLDL | 3 |
network-rewiring
|
| 681L | EEQ[F/L]FKTKSQGPSLDL | 4 |
distal
|
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