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Mutation:
NT5C2 P503A
Summary
Isoform:
Position:
503
Ref:
P
Mutation:
A
PTM impact:
network-rewiring
PTM affected:
2
Kinases:
Clinical Information
Cancer types: (TCGA MC3)
LUAD
Cancer types: (PCAWG)
no data
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 502S
Affected site:
Position: 502
Residue: S
Type: phosphorylation
Only loss of PTM site:
CDK7 (probability p=0.883)
Site: 502S (phosphorylation)
Position in motif: 1
Other known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 501D | VDINEM[E/D]ESPLATRNR | 1 |
proximal
|
| 503A | VDINEMES[P/A]PLATRNR | 1 |
network-rewiring
|
PTM Site: 510T
Affected site:
Position: 510
Residue: T
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 510P | PLATRNR[T/P]TSVDFKDT | 0 |
direct
|
| 510I | PLATRNR[T/I]TSVDFKDT | 0 |
direct
|
| 512L | PLATRNRTS[V/L]VDFKDT | 2 |
proximal
|
| 509C | PLATRN[R/C]RTSVDFKDT | 1 |
proximal
|
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