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Mutation:
ARFGAP3 F421C
Summary
Clinical Information
Cancer types: (TCGA MC3)
no data
Cancer types: (PCAWG)
Ovary-AdenoCA
Disease Annotations: (ClinVar)
no data
Minor Allele Frequency: (ESP6500)
no data
Minor Allele Frequency: (1000 Genomes)
no data
PTM Site: 425K
Affected site:
Position: 425
Residue: K
Type: ubiquitination
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 431T | QKKFGNVKAISSD[M/T]MY | 6 |
distal
|
| 431I | QKKFGNVKAISSD[M/I]MY | 6 |
distal
|
| 420T | QK[K/T]KFGNVKAISSDMY | 5 |
distal
|
| 421C | QKK[F/C]FGNVKAISSDMY | 4 |
distal
|
PTM Site: 428S
Affected site:
Position: 428
Residue: S
Type: phosphorylation
Impact:
distalOther known mutations affecting this site
| Mutation | In sequence | Distance | Impact |
|---|---|---|---|
| 431T | FGNVKAISSD[M/T]MYFGR | 3 |
distal
|
| 431I | FGNVKAISSD[M/I]MYFGR | 3 |
distal
|
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